Selank

Selank

Selank is a synthetic heptapeptide analogue of tuftsin, extended with a Pro-Gly-Pro C-terminal sequence for enhanced stability. Developed for its anxiolytic and cognitive-enhancing properties, Selank is widely used for stress reduction, calm mental clarity, and memory support — without the sedating effects of conventional anxiolytics.

How It Works

Selank modulates multiple neurotransmitter systems to deliver its cognitive and anxiolytic benefits:

• GABA-A Modulation:: Enhances GABAergic inhibitory neurotransmission, producing anxiolytic effects without sedation

• Serotonin System:: Modulates serotonin transporter expression and serotonin metabolism in brain regions associated with mood and anxiety

• BDNF Expression:: Upregulates BDNF in hippocampal and cortical neurons, supporting memory and neuroplasticity

• Enkephalin Stabilization:: Inhibits enkephalin-degrading enzymes, increasing endogenous opioid peptide availability for stress modulation

• Memory Consolidation:: Supports contextual memory formation through hippocampal synaptic plasticity

Key Benefits

• Stress & Anxiety Reduction:: Calm, non-sedating anxiolytic effects

• Calm Focus:: Reduces anxiety while maintaining mental clarity and alertness

• Memory Enhancement:: Supports memory consolidation and recall

• Mood Support:: Modulates serotonin and GABA systems for balanced mood

Structural Properties

Selank has a molecular weight of 751.9 Da with the sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro (CAS: 129954-34-3). Purity ≥99.0%.

Quality and Purity

Supplied as a lyophilized powder with purity ≥99.0% verified by HPLC and mass spectrometry. Each vial contains 10 mg.

Storage

Store at −20°C. Stable for 24 months.